أحد أسئلة الدفعة 46

فرق آخر مهم بينهن

Barbiturates ?? cause hypothermia in grade 3

Cyclic antidepressants?? cause hyperthermia

**Barbiturates :
Metabolism primirly by hepatic enzymes to inactive metabolites except mephobarbital and methabarbital

Excretion
Long acting barbiturates ?? more dependent on renal excretion
Short & intermediate barbiturates urinary excretion is negligible

أمّا
** Cyclic antidepressants elimination entirely hepatic, little unchanged drug excreted in urine

امتحانات الجزئي عيون السنة اللي فاتت ??