https://x.com/davidbessis/status/1816459931995840984

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David Bessis (@davidbessis) on X

A simple math proof that math talent isn’t primarily driven by genetics. ***⤵️***

simple version:
https://health.ucsd.edu/news/press-releases/2020-04-15-when-damaged-adult-brain-repairs-itself-going-back-to-beginning

UC San Diego Health

When Damaged, the Adult Brain Repairs Itself by Going Back to the Beginning

When adult brain cells are injured, they revert to an embryonic state, say researchers at UC San Diego School of Medicine. In their newly adopted immature state, the cells become capable of re-growing new connections that, under the right conditions, can…

https://www.nature.com/articles/s41586-020-2200-5

«Injured adult neurons regress to an embryonic transcriptional growth state» by G. H. D. Poplawski et al (2020)

Grafts of spinal-cord-derived neural progenitor cells (NPCs) enable the robust regeneration of corticospinal axons and restore forelimb function after spinal cord injury1; however, the molecular mechanisms that underlie this regeneration are unknown. Here we perform translational profiling specifically of corticospinal tract (CST) motor neurons in mice, to identify their ‘regenerative transcriptome’ after spinal cord injury and NPC grafting. Notably, both injury alone and injury combined with NPC grafts elicit virtually identical early transcriptomic responses in host CST neurons. However, in mice with injury alone this regenerative transcriptome is downregulated after two weeks, whereas in NPC-grafted mice this transcriptome is sustained. The regenerative transcriptome represents a reversion to an embryonic transcriptional state of the CST neuron. The huntingtin gene (Htt) is a central hub in the regeneration transcriptome; deletion of Htt significantly attenuates regeneration, which shows that Htt has a key role in neural plasticity after injury.

Nature

Injured adult neurons regress to an embryonic transcriptional growth state

Nature - In mouse models of central nervous system injury, Htt is shown to be a key component of the regulatory program associated with reversion of the neuronal transcriptome to a less-mature state.

https://www.oxfordstudent.com/2024/04/20/oxford-shuts-down-elon-musk-funded-future-of-humanity-institute/

oh shit

The Oxford Student

Oxford shuts down Elon Musk-funded Future of Humanity Institute – The Oxford Student

The Future of Humanity Institute (FHI) was shut down by the Faculty of Philosophy on April 16th after 19 years of operation. The Institute was founded in 2005 and was run by Swedish-born philosopher Nick Bostrom, known for his work popularizing the theory…

https://www.youtube.com/watch?v=aSO9lfWf2wM

YouTube

"He just does math all day"