Correct Answer - D
Ans. is 'd i.e., All of the above

Causes of cherry red spot
GM2 gangliosidoses (Tay sachs & sandhoff)
Hurler's syndrome
GM1 gangliosidoses
Cryoglobulinemia
Niemann - Pick's disease
Laber's congenital amaurosis
Gaucher's disease
Sialidosis (galactosialidosis)
Metachromatic leukodystrophy
Mucopolysacharidosis VII
Central retinal artery occlusion (CRAO)
Multiple sulfatase deficiency
Trauma (Berlin's edema / commotio retinae)
Poisoning :- Carbon mono-oxide, methanol
Quinine and Dapsone
Shprintzen-Goldberg syndrome
Farber's disease
Hallervorden Spatz disease
Goldberg's disease
Rarely in krabbe's disease

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Correct Answer - D

The main pathological changes in Keratoconus are thinning and
ectasia of the lens which occur as a result of defective synthesis of
mucopolysaccharide and collagen tissue.

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Correct Answer - D

Plasma levels of cholesterol and triglyceride are extremely low in
this disorder, and chylomicrons.

Abetalipoproteinemia usually
presents in early childhood with diarrhea and failure to thrive.

The neurological manifestations like decreased distal lower
extremity vibratory and proprioceptive sense, dysmetria, ataxia, and the development of a spastic gait, often by the third or fourth decade.

Patients also develop a progressive pigmented retinopathy
presenting with decreased night and color vision.
Ref: Harrisons Principles of Internal Medicine, 18th Edition, Page
3153

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Correct Answer - D
Answer- D. All the above

Fine tremors are noted when a limb is held in an antigravity posture
They are noted in situations of catecholamine excess such as
anxiety states, thyrotoxicosis, hypoglycemia and in alcoholism and excess smoking.

They are also noted after ingestion of drugs like caffeine, salbutamol, theophylline, amphetamine, tricyclic antidepressants, Lithium, valproate, steroids, and in mercury poisoning.

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Correct Answer - C
Answer- C. Tremors

Parkinsonism is a progressive degenerative, extrapyramidal disorder of muscle movement, due to dysfunction in basal ganglia,
comprising four cardinal features
Bradykinesia or hypokinesia
Muscle rigidity
Resting tremor

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